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There are two types of trains you can take from Madrid to Seville: high speed trains and regular trains.
High Speed Trains from Madrid to Seville
High speed ‘AVE’ trains run regularly throughout the day from Madrid Atocha train station to Seville Santa Justa train station.
Trains leave Madrid for Seville 1-3 times an hour throughout the day, with more frequent departures during peak times and less frequent departures during off-peak times. Trains from Seville to Madrid return at similar intervals.
The total train time from Madrid to Seville is 2.5 hours.
The cost of a round-trip train ticket from Madrid to Seville varies depending on the time of the train and how far in advance you book your ticket. The standard advance-booking fare is around 75 EUR.
Non-’AVE’ Trains from Madrid to Seville
Slower ‘European Train’ trains from Madrid to Seville run several times a day. Trains depart from Madrid Atocha train station and arrive at Seville Santa Justa train station.
The total train trip from Madrid to Seville on these trains takes 3h13m and costs around 59.00 EUR for standard class.
Regional trains no longer run on the route as Renfe is trying to push everyone onto the Ave service.