Traveling by train from Prague to Frankfurt is a great way to get from the capital of the Czech Republic to the major city in Germany when you are visiting Europe.
Overnight trains between these cities depart from Prague’s Hlavni Nadrazi train station. It is the central station in the capital and can be reached by all forms of transportation. Trains arrive at the Frankfurt Sud station, where many long-distance services terminate.
Trains from Prague to Frankfurt are run by City Night Line, which runs overnight trains between major cities throughout Europe. If you need to travel during the day, you can take a bus to Nuremberg and change there for a train to Frankfurt.
The overnight train journey takes 9 hours and 30 minutes. Services arrive very early in the morning, so make sure to have a plan for when you get to Germany.
The cost of a train from Prague to Frankfurt varies depending on what kind of seat you choose. Fares start at 69 euros one-way if you book online well in advance.