Eurostar trains from Avignon to London run directly from Avignon Centre train station to London St. Pancras train station during the summer season.
This year the summer season runs from 28 June to 13 September 2014. It has been extended from last year due to the popularity of the service, and plans are in the works to make the service available year-round from 2015.
Eurostar trains depart Avignon Centre station on Saturdays at 16:47 and arrive at London St. Pancras at 21:11.
Returning Eurostar trains from London to Avignon depart London St. Pancras on Saturdays at 7:17 and arrive in Avignon at 13:47.
During the off-season, Eurostar trains from Avignon to London run via Lille. You will have to change trains at Lille Europe train station in order to reach London from Avignon.